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This is a non-core endpoint: only basic statistics are computed.

Agent resistant to penicillin and related antibiotics

U22_AGENT_RESISTANT_PENICILLIN_RELATED_ANTIBI

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 U80
  • Cause of death: ICD-10 U80

2 out of 7 registries used, show all original rules.

11

4. Check minimum number of events

None

11

5. Include endpoints

None

11

6. Filter based on genotype QC (FinnGen only)

11

Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 U8

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 91 46 45
Only index persons 87 43 44
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population - 54.59 63.17
Only index persons 61.47 59.63 63.26

-FinnGen-

Key figures

All Female Male
Number of individuals 11 9 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 65.15 62.47 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Association

Association between endpoint U22_AGENT_RESISTANT_PENICILLIN_RELATED_ANTIBI and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have U22_AGENT_RESISTANT_PENICILLIN_RELATED_ANTIBI.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: U22_AGENT_RESISTANT_PENICILLIN_RELATED_ANTIBI – Agent resistant to penicillin and related antibiotics

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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