No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
15340 |
4. Check minimum number of eventsNone |
15340 |
5. Include endpointsNone |
15340 |
6. Filter based on genotype QC (FinnGen only) |
14824 |
Control definitions (FinnGen only)
Control exclude
ST19_INJURI_SHOUL_UPPER_ARM
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S4
Name in latin
Fractura in regione deltoidea/brachii
Similar endpoints
↥List of similar endpoints to
Fracture of shoulder and upper arm
based on the number of shared cases.
Similar with more cases:
- Injuries to the shoulder and upper arm
- Injury, poisoning and certain other consequences of external causes
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 209130 | 106621 | 101744 |
| Only index persons | 184227 | 93641 | 90586 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.94 | 3.05 | 2.84 |
| Only index persons | 3.45 | 3.44 | 3.46 |
| Median age at first event (years) | |||
| Whole population | 49.99 | 63.24 | 35.99 |
| Only index persons | 49.65 | 62.81 | 36.04 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 14824 | 8325 | 6499 |
| Unadjusted period prevalence (%) | 3.27 | 3.27 | 3.26 |
| Median age at first event (years) | 57.69 | 60.76 | 53.75 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint ST19_FRACT_SHOUL_UPPER_ARM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ST19_FRACT_SHOUL_UPPER_ARM | 1.646 [1.5, 1.8] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.018 |
During the follow-up period (1.1.1998 — 31.12.2019), 25839 out of 91079 females with ST19_FRACT_SHOUL_UPPER_ARM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ST19_FRACT_SHOUL_UPPER_ARM | 2.28 [2.05, 2.54] | < 0.001 |
| Birth year | 0.981 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 15210 out of 88311 males with ST19_FRACT_SHOUL_UPPER_ARM died.
Mortality risk
Mortality risk for people of age
years, who have ST19_FRACT_SHOUL_UPPER_ARM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.128% | 0.335% |
| 5 | 0.739% | 2.046% |
| 10 | 1.967% | 5.141% |
| 15 | 3.949% | 9.273% |
| 20 | 6.591% | 15.829% |
Relationships between endpoints
↥Index endpoint: ST19_FRACT_SHOUL_UPPER_ARM – Fracture of shoulder and upper arm
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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