No definition available.
Fracture of rib(s), sternum and thoracic spine
EFO MESH Endpoint Browser PheWeb
ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
11834 |
4. Check minimum number of eventsNone |
11834 |
5. Include endpointsNone |
11834 |
6. Filter based on genotype QC (FinnGen only) |
11410 |
Control definitions (FinnGen only)
Control exclude
ST19_INJURI_THORAX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S2
Name in latin
Fractura costae/costarum, sterni et/sive partis thoracicae columnae vertebralis
Similar endpoints
↥List of similar endpoints to
Fracture of rib(s), sternum and thoracic spine
based on the number of shared cases.
Similar with more cases:
- Injuries to the thorax
- Injury, poisoning and certain other consequences of external causes
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 115072 | 45013 | 69354 |
| Only index persons | 104108 | 40652 | 63456 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.68 | 1.29 | 1.94 |
| Only index persons | 2.06 | 1.49 | 2.42 |
| Median age at first event (years) | |||
| Whole population | 62.07 | 70.42 | 56.62 |
| Only index persons | 60.75 | 68.52 | 55.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 11410 | 4514 | 6896 |
| Unadjusted period prevalence (%) | 2.79 | 1.77 | 3.46 |
| Median age at first event (years) | 61.73 | 61.77 | 61.71 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE | 1.695 [1.53, 1.88] | < 0.001 |
| Birth year | 0.993 [0.99, 1.0] | 0.097 |
During the follow-up period (1.1.1998 — 31.12.2019), 12809 out of 37101 females with ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE | 1.976 [1.78, 2.2] | < 0.001 |
| Birth year | 0.984 [0.98, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 15266 out of 57752 males with ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE died.
Mortality risk
Mortality risk for people of age
years, who have ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.167% | 0.321% |
| 5 | 0.902% | 1.905% |
| 10 | 2.228% | 4.832% |
| 15 | 4.229% | 9.176% |
| 20 | 7.552% | 15.221% |
Relationships between endpoints
↥Index endpoint: ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE – Fracture of rib(s), sternum and thoracic spine
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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