No definition available.
Fractures involving multiple body regions
ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
67 |
4. Check minimum number of eventsNone |
67 |
5. Include endpointsNone |
67 |
6. Filter based on genotype QC (FinnGen only) |
66 |
Control definitions (FinnGen only)
Control exclude
ST19_INJURI_INVOLVI_MULTIPLE_BODY_REGIONS
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
T0[0-7]
Name in latin
Fracturae regionum multarum corporis
Similar endpoints
↥List of similar endpoints to
Fractures involving multiple body regions
based on the number of shared cases.
Similar with more cases:
- Injuries involving multiple body regions
- Accidents
- External causes of morbidity and mortality
- Injury, poisoning and certain other consequences of external causes
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 824 | 329 | 486 |
| Only index persons | 693 | 273 | 420 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 53.75 | 63.34 | 46.96 |
| Only index persons | 52.08 | 60.94 | 46.32 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 66 | 23 | 43 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 50.46 | 56.06 | 47.47 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS | 1.38 [0.97, 1.97] | 0.075 |
| Birth year | 0.996 [0.99, 1.0] | 0.376 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 246 females with ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS | 1.784 [1.18, 2.69] | 0.006 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 369 males with ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS died.
Mortality risk
Mortality risk for people of age
years, who have ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.161% | 0.346% |
| 5 | 0.839% | 2.057% |
| 10 | 2.117% | 4.647% |
| 15 | 4.204% | 8.732% |
| 20 | 7.137% | 14.969% |
Relationships between endpoints
↥Index endpoint: ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS – Fractures involving multiple body regions
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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