No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
14536 |
4. Check minimum number of eventsNone |
14536 |
5. Include endpointsNone |
14536 |
6. Filter based on genotype QC (FinnGen only) |
14046 |
Control definitions (FinnGen only)
Control exclude
R18_SYMPTOMS_SIGNS_INVOLVI_URINARY_SYSTEM
Extra metadata
Level in the ICD hierarchy
3
Special
URINERETENTION
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
R30-R39
Name in latin
Retentio urinae
Similar endpoints
↥List of similar endpoints to
Retention of urine
based on the number of shared cases.
Similar with more cases:
- Symptoms and signs involving the urinary system
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 130594 | 30375 | 98621 |
| Only index persons | 106312 | 25977 | 80335 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.30 | 0.87 | 2.76 |
| Only index persons | 2.55 | 0.95 | 3.07 |
| Median age at first event (years) | |||
| Whole population | 71.99 | 69.19 | 72.80 |
| Only index persons | 70.90 | 67.12 | 72.12 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 14046 | 3288 | 10758 |
| Unadjusted period prevalence (%) | 4.44 | 1.29 | 5.40 |
| Median age at first event (years) | 68.87 | 58.86 | 71.93 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint R18_RETEN_URINE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| R18_RETEN_URINE | 2.114 [1.91, 2.34] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.019 |
During the follow-up period (1.1.1998 — 31.12.2019), 8761 out of 23480 females with R18_RETEN_URINE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| R18_RETEN_URINE | 1.954 [1.76, 2.17] | < 0.001 |
| Birth year | 0.984 [0.98, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 37950 out of 77816 males with R18_RETEN_URINE died.
Mortality risk
Mortality risk for people of age
years, who have R18_RETEN_URINE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.165% | 0.372% |
| 5 | 1.217% | 1.993% |
| 10 | 2.776% | 4.779% |
| 15 | 5.002% | 8.751% |
| 20 | 8.499% | 14.307% |
Relationships between endpoints
↥Index endpoint: R18_RETEN_URINE – Retention of urine
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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