No definition available.
Other congenital malformations of upper alimentary tract
Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
224 |
4. Check minimum number of eventsNone |
224 |
5. Include endpointsNone |
224 |
6. Filter based on genotype QC (FinnGen only) |
218 |
Control definitions (FinnGen only)
Control exclude
Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q3[8-9]|Q4[0-5]
Name in latin
Aliae malformationes congenitae tractus digestorii superioris
Similar endpoints
↥List of similar endpoints to
Other congenital malformations of upper alimentary tract
based on the number of shared cases.
Similar with more cases:
- Other congenital malformations of the digestive system
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2520 | 841 | 1677 |
| Only index persons | 1862 | 650 | 1212 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.02 | 0.05 |
| Only index persons | 0.04 | 0.02 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 5.28 | 15.36 | 0.17 |
| Only index persons | 15.21 | 41.69 | 1.01 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 218 | 100 | 118 |
| Unadjusted period prevalence (%) | 0.05 | 0.04 | 0.06 |
| Median age at first event (years) | 61.97 | 58.70 | 64.75 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT | 1.843 [1.4, 2.43] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.266 |
During the follow-up period (1.1.1998 — 31.12.2019), 112 out of 751 females with Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT | 2.23 [1.68, 2.95] | < 0.001 |
| Birth year | 0.985 [0.97, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 167 out of 1492 males with Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT died.
Mortality risk
Mortality risk for people of age
years, who have Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.224% | 0.399% |
| 5 | 1.109% | 2.275% |
| 10 | 2.602% | 5.744% |
| 15 | 5.149% | 10.659% |
| 20 | 8.668% | 17.596% |
Relationships between endpoints
↥Index endpoint: Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT – Other congenital malformations of upper alimentary tract
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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