No definition available.
Other congenital malformations of peripheral vascular system
EFO MESH Endpoint Browser PheWeb
Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
425 |
4. Check minimum number of eventsNone |
425 |
5. Include endpointsNone |
425 |
6. Filter based on genotype QC (FinnGen only) |
411 |
Control definitions (FinnGen only)
Control exclude
Q17_CONGEN_MALFO_CIRCULATO_SYSTEM
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q2
Name in latin
Aliae malformationes congenitae systematis vascularis peripherici
Similar endpoints
↥List of similar endpoints to
Other congenital malformations of peripheral vascular system
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of the circulatory system
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3588 | 2038 | 1530 |
| Only index persons | 3103 | 1810 | 1293 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.04 |
| Only index persons | 0.06 | 0.07 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 27.46 | 30.77 | 22.92 |
| Only index persons | 31.03 | 32.77 | 28.60 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 411 | 271 | 140 |
| Unadjusted period prevalence (%) | 0.09 | 0.11 | 0.07 |
| Median age at first event (years) | 43.52 | 39.93 | 50.45 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM | 1.126 [0.85, 1.5] | 0.416 |
| Birth year | 0.994 [0.99, 1.0] | 0.189 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 1690 females with Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM | 1.198 [0.87, 1.65] | 0.266 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 1287 males with Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM died.
Mortality risk
Mortality risk for people of age
years, who have Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.135% | 0.224% |
| 5 | 0.647% | 1.384% |
| 10 | 1.645% | 3.654% |
| 15 | 3.268% | 6.451% |
| 20 | 5.809% | 10.974% |
Relationships between endpoints
↥Index endpoint: Q17_OTHER_CONGEN_MALFO_PERIP_VASCULAR_SYSTEM – Other congenital malformations of peripheral vascular system
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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