No definition available.
Slow fetal growth and fetal malnutrition
P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
195 |
4. Check minimum number of eventsNone |
195 |
5. Include endpointsNone |
195 |
6. Filter based on genotype QC (FinnGen only) |
181 |
Control definitions (FinnGen only)
Control exclude
P16_DISORD_RELATED_LENGTH_GESTATION_FETAL_GROWTH
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P0[5-8]
Name in latin
Crescentia tarda et malnutritio fetalis
Similar endpoints
↥List of similar endpoints to
Slow fetal growth and fetal malnutrition
based on the number of shared cases.
Similar with more cases:
- Disorders related to length of gestation and fetal growth
- Certain conditions originating in the perinatal period
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12946 | 6759 | 6182 |
| Only index persons | 6781 | 3568 | 3213 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.18 | 0.19 | 0.17 |
| Only index persons | 0.13 | 0.13 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 0.01 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 181 | 111 | 70 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 0.00 | 0.00 | 0.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION | 6.474 [4.98, 8.41] | < 0.001 |
| Birth year | 0.997 [0.99, 1.0] | 0.407 |
During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 6317 females with P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION | 3.741 [2.92, 4.79] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 5727 males with P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION died.
Mortality risk
Mortality risk for people of age
years, who have P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.569% | 0.49% |
| 5 | 3.842% | 3.819% |
| 10 | 8.574% | 10.069% |
| 15 | 17.236% | 18.695% |
| 20 | 30.123% | 31.154% |
Relationships between endpoints
↥Index endpoint: P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION – Slow fetal growth and fetal malnutrition
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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