No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
200 |
4. Check minimum number of eventsNone |
200 |
5. Include endpoints |
200 |
6. Filter based on genotype QC (FinnGen only) |
193 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P
Name in latin
Traumata intranatalia
Birth trauma
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9791 | 4219 | 5565 |
| Only index persons | 5628 | 2503 | 3125 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.12 | 0.16 |
| Only index persons | 0.11 | 0.09 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 0.05 | 0.04 | 0.02 |
| Only index persons | 0.05 | 0.05 | 0.04 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 193 | 111 | 82 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 2.19 | 3.02 | 1.07 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint P16_BIRTH_TRAUMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_BIRTH_TRAUMA | 1.543 [1.13, 2.11] | 0.007 |
| Birth year | 0.996 [0.99, 1.0] | 0.359 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 3961 females with P16_BIRTH_TRAUMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| P16_BIRTH_TRAUMA | 1.873 [1.45, 2.41] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 95 out of 5252 males with P16_BIRTH_TRAUMA died.
Mortality risk
Mortality risk for people of age
years, who have P16_BIRTH_TRAUMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.143% | 0.373% |
| 5 | 0.858% | 2.08% |
| 10 | 2.118% | 5.169% |
| 15 | 4.203% | 10.013% |
| 20 | 7.55% | 16.362% |
Relationships between endpoints
↥Index endpoint: P16_BIRTH_TRAUMA – Birth trauma
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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