Alcohol related diseases, tilastokeskus definition, death only

OFFICIAL_TILASTOKESKUS_DEATH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

2500

6. Filter based on genotype QC (FinnGen only)

2436

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 108371 18176 87308
Only index persons 39775 7738 32037
Unadjusted period prevalence (%)
Whole population 2.13 0.52 2.44
Only index persons 1.04 0.28 1.22
Median age at first event (years)
Whole population 55.96 57.22 55.61
Only index persons 61.60 62.13 61.47

-FinnGen-

Key figures

All Female Male
Number of individuals 2436 328 2108
Unadjusted period prevalence (%) 0.93 0.13 1.06
Median age at first event (years) 64.76 60.44 65.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint OFFICIAL_TILASTOKESKUS_DEATH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have OFFICIAL_TILASTOKESKUS_DEATH.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: OFFICIAL_TILASTOKESKUS_DEATH – Alcohol related diseases, tilastokeskus definition, death only

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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