Uterine polyps

N14_UTER_POLYP

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N84.1
  • Cause of death: ICD-10 N84.1

2 out of 7 registries used, show all original rules.

3665

4. Check minimum number of events

None

3665

5. Include endpoints

None

3665

6. Filter based on genotype QC (FinnGen only)

3510

Control definitions (FinnGen only)

Control exclude N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF6

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 25878 25878 -
Only index persons 25170 25170 -
Unadjusted period prevalence (%)
Whole population 0.74 0.74 -
Only index persons 0.93 0.93 -
Median age at first event (years)
Whole population - 51.86 -
Only index persons - 51.57 -

-FinnGen-

Key figures

All Female Male
Number of individuals 3510 3510 -
Unadjusted period prevalence (%) 1.38 1.38 -
Median age at first event (years) 51.57 51.57 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint N14_UTER_POLYP and mortality.

Females

Parameter HR [95% CI] p-value
N14_UTER_POLYP 0.874 [0.8, 0.95] 0.002
Birth year 0.994 [0.99, 1.0] 0.195

During the follow-up period (1.1.1998 — 31.12.2019), 2141 out of 22221 females with N14_UTER_POLYP died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_UTER_POLYP.

N-year risk Females Males
1 0.11% No data
5 0.544% No data
10 1.323% No data
15 2.509% No data
20 4.363% No data

Relationships between endpoints

Index endpoint: N14_UTER_POLYP – Uterine polyps

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data