Unspecified renal colic

N14_RENALCOLNAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N23
  • Cause of death: ICD-10 N23

2 out of 7 registries used, show all original rules.

202

4. Check minimum number of events

None

202

5. Include endpoints

None

202

6. Filter based on genotype QC (FinnGen only)

188

Control definitions (FinnGen only)

Control exclude N14_UROLITHIASIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N20-N23
Name in latin Colica renalis non specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1579 646 917
Only index persons 1527 638 889
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.03
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 51.25 48.54 53.44
Only index persons 51.02 48.38 52.91

-FinnGen-

Key figures

All Female Male
Number of individuals 188 89 99
Unadjusted period prevalence (%) 0.04 0.03 0.05
Median age at first event (years) 54.06 51.43 56.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint N14_RENALCOLNAS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
N14_RENALCOLNAS 0.872 [0.68, 1.11] 0.268
Birth year 0.99 [0.98, 1.0] 0.039

During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 836 males with N14_RENALCOLNAS died.

Mortality risk

Mortality risk for people of age

years, who have N14_RENALCOLNAS.

N-year risk Females Males
1 No data 0.145%
5 No data 1.102%
10 No data 2.804%
15 No data 5.38%
20 No data 9.006%

Relationships between endpoints

Index endpoint: N14_RENALCOLNAS – Unspecified renal colic

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data