No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
14675 |
4. Check minimum number of eventsNone |
14675 |
5. Include endpointsNone |
14675 |
6. Filter based on genotype QC (FinnGen only) |
14206 |
Control definitions (FinnGen only)
Control exclude
N14_FEMALEGENNONINF
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N95
Name in latin
Haemorrhagia postmenopausalis
Similar endpoints
↥List of similar endpoints to
Postmenopausal bleeding
based on the number of shared cases.
Similar with more cases:
- Noninflammatory disorders of female genital tract
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 113455 | 113455 | - |
| Only index persons | 102090 | 102090 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 3.25 | 3.25 | - |
| Only index persons | 3.75 | 3.75 | - |
| Median age at first event (years) | |||
| Whole population | - | 60.40 | - |
| Only index persons | - | 59.62 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 14206 | 14206 | - |
| Unadjusted period prevalence (%) | 5.58 | 5.58 | - |
| Median age at first event (years) | 58.56 | 58.56 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint N14_POSTMENBLEED and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_POSTMENBLEED | 1.259 [1.17, 1.35] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.043 |
During the follow-up period (1.1.1998 — 31.12.2019), 17654 out of 79472 females with N14_POSTMENBLEED died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_POSTMENBLEED.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.104% | No data |
| 5 | 0.637% | No data |
| 10 | 1.526% | No data |
| 15 | 3.143% | No data |
| 20 | 5.467% | No data |
Relationships between endpoints
↥Index endpoint: N14_POSTMENBLEED – Postmenopausal bleeding
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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