Other and unspecified noninflammatory disorders of ovary, fallopian tube and broad ligament

N14_OTHNONINFOVA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N83.8, N83.9
  • Hospital discharge: ICD-9 6206
  • Cause of death: ICD-10 N83.8, N83.9
  • Cause of death: ICD-9 6206

2 out of 7 registries used, show all original rules.

1000

4. Check minimum number of events

None

1000

5. Include endpoints

None

1000

6. Filter based on genotype QC (FinnGen only)

959

Control definitions (FinnGen only)

Control exclude N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6581 6581 -
Only index persons 6474 6474 -
Unadjusted period prevalence (%)
Whole population 0.19 0.19 -
Only index persons 0.24 0.24 -
Median age at first event (years)
Whole population - 39.88 -
Only index persons - 39.75 -

-FinnGen-

Key figures

All Female Male
Number of individuals 959 959 -
Unadjusted period prevalence (%) 0.38 0.38 -
Median age at first event (years) 43.10 43.10 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint N14_OTHNONINFOVA and mortality.

Females

Parameter HR [95% CI] p-value
N14_OTHNONINFOVA 1.184 [1.02, 1.38] 0.029
Birth year 0.994 [0.99, 1.0] 0.195

During the follow-up period (1.1.1998 — 31.12.2019), 317 out of 5661 females with N14_OTHNONINFOVA died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_OTHNONINFOVA.

N-year risk Females Males
1 0.093% No data
5 0.606% No data
10 1.766% No data
15 3.405% No data
20 5.588% No data

Relationships between endpoints

Index endpoint: N14_OTHNONINFOVA – Other and unspecified noninflammatory disorders of ovary, fallopian tube and broad ligament

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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