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Hydrocele

DOID EFO Endpoint Browser PheWeb

N14_HYDROCELE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only males

207946

2. Check conditions

None

207946

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N43
  • Hospital discharge: ICD-9 — 603
  • Hospital discharge: ICD-8 — 603
  • Hospital discharge: excluded ICD-9 — N434
  • Cause of death: ICD-10 — N43
  • Cause of death: ICD-9 — 603
  • Cause of death: ICD-8 — 603
  • Cause of death: excluded ICD-9 — N434

2 out of 7 registries used, show all original rules.

6494

4. Check minimum number of events

None

6494

5. Include endpoints

None

6494

6. Filter based on genotype QC (FinnGen only)

6251

Control definitions (FinnGen only)

Control exclude N14_MALEGEN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N40-N51
Name in latin Hydrocele et spermatocele

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 69006 - 69006
Only index persons 57749 - 57749
Unadjusted period prevalence (%)
Whole population 1.93 - 1.93
Only index persons 2.20 - 2.20
Median age at first event (years)
Whole population - - 51.68
Only index persons - - 50.42

-FinnGen-

Key figures

All Female Male
Number of individuals 6251 - 6251
Unadjusted period prevalence (%) 3.14 - 3.14
Median age at first event (years) 57.49 - 57.49

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint N14_HYDROCELE and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
N14_HYDROCELE 0.942 [0.87, 1.02] 0.153
Birth year 0.986 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 6952 out of 42046 males with N14_HYDROCELE died.

Mortality risk

Mortality risk for people of age

years, who have N14_HYDROCELE.

N-year risk Females Males
1 No data 0.175%
5 No data 1.108%
10 No data 2.649%
15 No data 5.024%
20 No data 8.481%

Relationships between endpoints

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Index endpoint: N14_HYDROCELE – Hydrocele

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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