No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
4492 |
4. Check minimum number of eventsNone |
4492 |
5. Include endpointsNone |
4492 |
6. Filter based on genotype QC (FinnGen only) |
4363 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N99-N99
Name in latin
Morbositates systematis urogenitalis post interventiones, non alibi classificatae
Other disorders of the genitourinary system
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 28395 | 21899 | 6291 |
| Only index persons | 25558 | 20942 | 4616 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.52 | 0.63 | 0.18 |
| Only index persons | 0.66 | 0.77 | 0.18 |
| Median age at first event (years) | |||
| Whole population | 65.09 | 63.14 | 71.69 |
| Only index persons | 64.02 | 62.65 | 70.21 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4363 | 3595 | 768 |
| Unadjusted period prevalence (%) | 1.23 | 1.41 | 0.39 |
| Median age at first event (years) | 62.37 | 60.70 | 70.17 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint N14_GENITOUROTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_GENITOUROTH | 0.864 [0.79, 0.95] | 0.002 |
| Birth year | 0.998 [0.99, 1.01] | 0.558 |
During the follow-up period (1.1.1998 — 31.12.2019), 2534 out of 18009 females with N14_GENITOUROTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_GENITOUROTH | 1.247 [1.12, 1.39] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 1941 out of 4252 males with N14_GENITOUROTH died.
Mortality risk
Mortality risk for people of age
years, who have N14_GENITOUROTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.099% | 0.27% |
| 5 | 0.561% | 1.473% |
| 10 | 1.346% | 3.633% |
| 15 | 2.567% | 6.953% |
| 20 | 4.602% | 11.196% |
Relationships between endpoints
↥Index endpoint: N14_GENITOUROTH – Other disorders of the genitourinary system
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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