No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2888 |
4. Check minimum number of eventsNone |
2888 |
5. Include endpointsNone |
2888 |
6. Filter based on genotype QC (FinnGen only) |
2768 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Amenorrhoea based on the number of shared cases.
Similar with more cases:
- Polycystic ovarian syndrome, consortium definition
- Noninflammatory disorders of female genital tract
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 23028 | 23028 | - |
Only index persons | 22269 | 22269 | - |
Unadjusted period prevalence (%) | |||
Whole population | 0.66 | 0.66 | - |
Only index persons | 0.82 | 0.82 | - |
Median age at first event (years) | |||
Whole population | - | 23.76 | - |
Only index persons | - | 23.55 | - |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 2768 | 2768 | - |
Unadjusted period prevalence (%) | 1.09 | 1.09 | - |
Median age at first event (years) | 26.52 | 26.52 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint N14_AMENORRHEAPRIM and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
N14_AMENORRHEAPRIM | 2.788 [2.41, 3.22] | < 0.001 |
Birth year | 0.989 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 506 out of 17416 females with N14_AMENORRHEAPRIM died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_AMENORRHEAPRIM.N-year risk | Females | Males |
---|---|---|
1 | 0.183% | No data |
5 | 1.321% | No data |
10 | 3.559% | No data |
15 | 6.383% | No data |
20 | 11.133% | No data |
Relationships between endpoints
↥Index endpoint: N14_AMENORRHEAPRIM – Amenorrhoea
GWS hits: 1