skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1397 |
4. Check minimum number of eventsNone |
1397 |
5. Include endpointsNone |
1397 |
6. Filter based on genotype QC (FinnGen only) |
1328 |
Control definitions (FinnGen only)
Control exclude
L12_DERMATITISECZEMA
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L27
Name in latin
Dermatitis ex cibo devorato
Similar endpoints
↥List of similar endpoints to
Dermatitis due to ingested food
based on the number of shared cases.
Similar with more cases:
- Dermatitis and eczema
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 54667 | 23247 | 31410 |
| Only index persons | 37769 | 16243 | 21526 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.79 | 0.67 | 0.88 |
| Only index persons | 0.73 | 0.60 | 0.82 |
| Median age at first event (years) | |||
| Whole population | 1.20 | 1.28 | 1.14 |
| Only index persons | 1.19 | 1.31 | 1.10 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1328 | 845 | 483 |
| Unadjusted period prevalence (%) | 0.30 | 0.33 | 0.24 |
| Median age at first event (years) | 3.52 | 4.43 | 1.93 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_FOODDERMAT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_FOODDERMAT | 1.166 [0.82, 1.66] | 0.397 |
| Birth year | 0.994 [0.99, 1.0] | 0.143 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 20631 females with L12_FOODDERMAT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_FOODDERMAT | 1.004 [0.79, 1.28] | 0.975 |
| Birth year | 0.99 [0.98, 1.0] | 0.035 |
During the follow-up period (1.1.1998 — 31.12.2019), 84 out of 27933 males with L12_FOODDERMAT died.
Mortality risk
Mortality risk for people of age
years, who have L12_FOODDERMAT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.097% | 0.229% |
| 5 | 0.584% | 1.365% |
| 10 | 1.745% | 3.324% |
| 15 | 3.17% | 6.496% |
| 20 | 5.573% | 10.774% |
Relationships between endpoints
↥Index endpoint: L12_FOODDERMAT – Dermatitis due to ingested food
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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