No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersPre-conditions: EVENT_AGE <25 Registry filters:
3 out of 7 registries used, show all original rules. |
6005 |
4. Check minimum number of eventsNone |
6005 |
5. Include endpointsNone |
6005 |
6. Filter based on genotype QC (FinnGen only) |
5579 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Dental pulpitis 3
based on the number of shared cases.
Similar with more cases:
- Dental pulpitis 1
- Dental pulpitis 4
- Diseases of pulp and periapical tissues, including avohilmo
- Dental pulpitis 2
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 184630 | 87825 | 95853 |
| Only index persons | 158144 | 76364 | 81780 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.59 | 2.52 | 2.68 |
| Only index persons | 2.97 | 2.81 | 3.12 |
| Median age at first event (years) | |||
| Whole population | 17.36 | 17.65 | 17.04 |
| Only index persons | 18.98 | 19.04 | 18.92 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 5579 | 4025 | 1554 |
| Unadjusted period prevalence (%) | 1.36 | 1.58 | 0.78 |
| Median age at first event (years) | 21.62 | 21.56 | 21.78 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_PULPITIS_3 and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PULPITIS_3 | 2.123 [1.53, 2.95] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.102 |
During the follow-up period (1.1.1998 — 31.12.2019), 146 out of 75065 females with K11_PULPITIS_3 died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PULPITIS_3 | 1.9 [1.55, 2.33] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 81260 males with K11_PULPITIS_3 died.
Mortality risk
Mortality risk for people of age
years, who have K11_PULPITIS_3.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.19% | 0.273% |
| 5 | 1.119% | 2.08% |
| 10 | 3.1% | 5.339% |
| 15 | 5.544% | 9.645% |
| 20 | 9.591% | 16.83% |
Relationships between endpoints
↥Index endpoint: K11_PULPITIS_3 – Dental pulpitis 3
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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