No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
111248 |
4. Check minimum number of eventsNone |
111248 |
5. Include endpointsNone |
111248 |
6. Filter based on genotype QC (FinnGen only) |
106479 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Dental pulpitis 1, only avohilmo
based on the number of shared cases.
Similar with more cases:
- Dental pulpitis 4, only avohilmo
- Dental pulpitis 1
- Dental pulpitis 4
- Diseases of pulp and periapical tissues, including avohilmo
- Dental pulpitis 2, only avohilmo
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1052117 | 514825 | 529035 |
| Only index persons | 1017238 | 502736 | 514502 |
| Unadjusted period prevalence (%) | |||
| Whole population | 14.72 | 14.75 | 14.78 |
| Only index persons | 19.07 | 18.48 | 19.64 |
| Median age at first event (years) | |||
| Whole population | 47.80 | 48.71 | 47.13 |
| Only index persons | 48.54 | 49.26 | 47.84 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 106479 | 61285 | 45194 |
| Unadjusted period prevalence (%) | 23.49 | 24.07 | 22.70 |
| Median age at first event (years) | 55.25 | 53.20 | 58.04 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_PULPITIS_1_ONLYAVO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PULPITIS_1_ONLYAVO | 0.95 [0.8, 1.13] | 0.571 |
| Birth year | 0.992 [0.98, 1.0] | 0.041 |
During the follow-up period (1.1.1998 — 31.12.2019), 11290 out of 435819 females with K11_PULPITIS_1_ONLYAVO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PULPITIS_1_ONLYAVO | 0.987 [0.83, 1.17] | 0.879 |
| Birth year | 0.989 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 17910 out of 446693 males with K11_PULPITIS_1_ONLYAVO died.
Mortality risk
Mortality risk for people of age
years, who have K11_PULPITIS_1_ONLYAVO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.064% | 0.116% |
| 5 | 0.434% | 0.961% |
| 10 | 1.185% | 2.544% |
| 15 | 2.21% | 5.016% |
| 20 | 3.819% | 8.684% |
Relationships between endpoints
↥Index endpoint: K11_PULPITIS_1_ONLYAVO – Dental pulpitis 1, only avohilmo
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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