No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
24913 |
4. Check minimum number of eventsNone |
24913 |
5. Include endpointsNone |
24913 |
6. Filter based on genotype QC (FinnGen only) |
23945 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF2
Death due to cardiac causes
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 729435 | 313742 | 395232 |
| Only index persons | 278653 | 139025 | 139628 |
| Unadjusted period prevalence (%) | |||
| Whole population | 10.45 | 8.99 | 11.04 |
| Only index persons | 5.22 | 5.11 | 5.33 |
| Median age at first event (years) | |||
| Whole population | 77.62 | 83.15 | 73.54 |
| Only index persons | 83.25 | 87.17 | 79.35 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 23945 | 6121 | 17824 |
| Unadjusted period prevalence (%) | 7.28 | 2.40 | 8.95 |
| Median age at first event (years) | 78.72 | 82.72 | 77.34 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint I9_K_CARDIAC and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have I9_K_CARDIAC.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: I9_K_CARDIAC – Death due to cardiac causes
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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