This is a non-core endpoint: only basic statistics are computed.
Polyneuropathy due to other toxic agents
G6_TOXICPOLY
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
23 |
4. Check minimum number of eventsNone |
23 |
5. Include endpointsNone |
23 |
6. Filter based on genotype QC (FinnGen only) |
22 |
Control definitions (FinnGen only)
Control exclude
G6_POLYNEU
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G62
Name in latin
Polyneuropathia toxica
Similar endpoints
↥List of similar endpoints to
Polyneuropathy due to other toxic agents
based on the number of shared cases.
Similar with more cases:
- Polyneuropathies and other disorders of the peripheral nervous system
- Neurological diseases
- Neurological diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 291 | 111 | 177 |
| Only index persons | 232 | 96 | 136 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 59.23 | 59.76 | 58.87 |
| Only index persons | 59.10 | 59.84 | 58.58 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 22 | 9 | 13 |
| Unadjusted period prevalence (%) | 0.01 | 0.00 | 0.01 |
| Median age at first event (years) | 58.37 | 55.14 | 60.61 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Association
Association between endpoint G6_TOXICPOLY and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_TOXICPOLY | 3.703 [2.35, 5.84] | < 0.001 |
| Birth year | 0.98 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 67 out of 137 males with G6_TOXICPOLY died.
Mortality risk
Mortality risk for people of age
years, who have G6_TOXICPOLY.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.653% |
| 5 | No data | 3.499% |
| 10 | No data | 8.612% |
| 15 | No data | 15.71% |
| 20 | No data | 24.986% |
Relationships between endpoints
↥Index endpoint: G6_TOXICPOLY – Polyneuropathy due to other toxic agents
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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