No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
266 |
4. Check minimum number of eventsNone |
266 |
5. Include endpointsNone |
266 |
6. Filter based on genotype QC (FinnGen only) |
251 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Drug-induced polyneuropathy based on the number of shared cases.
Similar with more cases:
- Polyneuropathies and other disorders of the peripheral nervous system
- Neurological diseases
- Neurological diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1549 | 841 | 700 |
Only index persons | 1345 | 745 | 600 |
Unadjusted period prevalence (%) | |||
Whole population | 0.02 | 0.02 | 0.02 |
Only index persons | 0.03 | 0.03 | 0.02 |
Median age at first event (years) | |||
Whole population | 62.86 | 64.41 | 60.97 |
Only index persons | 63.08 | 64.55 | 61.25 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 251 | 136 | 115 |
Unadjusted period prevalence (%) | 0.06 | 0.05 | 0.06 |
Median age at first event (years) | 62.53 | 63.58 | 61.28 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint G6_DRUGPOLY and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
G6_DRUGPOLY | 4.185 [3.26, 5.37] | < 0.001 |
Birth year | 0.996 [0.98, 1.01] | 0.502 |
During the follow-up period (1.1.1998 — 31.12.2019), 289 out of 698 females with G6_DRUGPOLY died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
G6_DRUGPOLY | 2.961 [2.28, 3.84] | < 0.001 |
Birth year | 0.99 [0.98, 1.0] | 0.032 |
During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 581 males with G6_DRUGPOLY died.
Mortality risk
Mortality risk for people of age
years, who have G6_DRUGPOLY.N-year risk | Females | Males |
---|---|---|
1 | 0.486% | 0.586% |
5 | 2.514% | 3.499% |
10 | 6.052% | 8.655% |
15 | 11.118% | 16.382% |
20 | 19.482% | 27.032% |
Relationships between endpoints
↥Index endpoint: G6_DRUGPOLY – Drug-induced polyneuropathy
GWS hits: -