This is a non-core endpoint: only basic statistics are computed.
Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
F5_ORGAMN
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
42 |
4. Check minimum number of eventsNone |
42 |
5. Include endpointsNone |
42 |
6. Filter based on genotype QC (FinnGen only) |
40 |
Control definitions (FinnGen only)
Control exclude
F5_ORGANIC
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
F04-F09
Name in latin
Syndroma amnesticum organicum non alcoholicum neque ab aliis substantiis psychotropicis inductum
Similar endpoints
↥List of similar endpoints to
Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
based on the number of shared cases.
Similar with more cases:
- Organic, including symptomatic, mental disorders
- Psychiatric diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 618 | 287 | 325 |
| Only index persons | 392 | 179 | 213 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 61.45 | 66.15 | 57.14 |
| Only index persons | 58.87 | 62.16 | 56.10 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 40 | 13 | 27 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 57.69 | 60.15 | 56.51 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Association
Association between endpoint F5_ORGAMN and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_ORGAMN | 2.828 [1.83, 4.37] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.35 |
During the follow-up period (1.1.1998 — 31.12.2019), 104 out of 182 females with F5_ORGAMN died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_ORGAMN | 3.338 [2.2, 5.06] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.056 |
During the follow-up period (1.1.1998 — 31.12.2019), 116 out of 217 males with F5_ORGAMN died.
Mortality risk
Mortality risk for people of age
years, who have F5_ORGAMN.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.201% | 0.622% |
| 5 | 1.661% | 3.742% |
| 10 | 4.01% | 10.027% |
| 15 | 7.3% | 18.649% |
| 20 | 13.199% | 29.477% |
Relationships between endpoints
↥Index endpoint: F5_ORGAMN – Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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