No definition available.
Other mental disorders due to brain damage and dysfunction and to physical disease
EFO MESH Endpoint Browser PheWeb
F5_MENTORG
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3849 |
4. Check minimum number of eventsNone |
3849 |
5. Include endpointsNone |
3849 |
6. Filter based on genotype QC (FinnGen only) |
3704 |
Control definitions (FinnGen only)
Control exclude
F5_ORGANIC
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F04-F09
Name in latin
Aliae perturbationes mentis ab laesione sive dysfunctione cerebri sive morbo somatico inductae
Similar endpoints
↥List of similar endpoints to
Other mental disorders due to brain damage and dysfunction and to physical disease
based on the number of shared cases.
Similar with more cases:
- Organic, including symptomatic, mental disorders
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 38591 | 19809 | 18505 |
| Only index persons | 33680 | 17739 | 15941 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.54 | 0.57 | 0.52 |
| Only index persons | 0.63 | 0.65 | 0.61 |
| Median age at first event (years) | |||
| Whole population | 71.15 | 74.89 | 67.27 |
| Only index persons | 71.89 | 75.22 | 68.19 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3704 | 1767 | 1937 |
| Unadjusted period prevalence (%) | 0.84 | 0.69 | 0.97 |
| Median age at first event (years) | 70.25 | 70.21 | 70.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_MENTORG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_MENTORG | 1.767 [1.59, 1.96] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.17 |
During the follow-up period (1.1.1998 — 31.12.2019), 5878 out of 15508 females with F5_MENTORG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_MENTORG | 2.012 [1.79, 2.26] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.017 |
During the follow-up period (1.1.1998 — 31.12.2019), 5467 out of 13461 males with F5_MENTORG died.
Mortality risk
Mortality risk for people of age
years, who have F5_MENTORG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.131% | 0.396% |
| 5 | 0.88% | 2.335% |
| 10 | 2.406% | 6.05% |
| 15 | 4.816% | 11.203% |
| 20 | 8.233% | 18.621% |
Relationships between endpoints
↥Index endpoint: F5_MENTORG – Other mental disorders due to brain damage and dysfunction and to physical disease
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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