No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
105 |
4. Check minimum number of eventsNone |
105 |
5. Include endpointsNone |
105 |
6. Filter based on genotype QC (FinnGen only) |
101 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Epileptic seizures related to drugs
based on the number of shared cases.
Similar with more cases:
- Epilepsy
- Episodal and paroxysmal disorders
- Neurological diseases
- Neurological diseases
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 693 | 270 | 422 |
| Only index persons | 667 | 264 | 403 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 34.78 | 37.41 | 33.12 |
| Only index persons | 34.73 | 37.19 | 33.12 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 101 | 45 | 56 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 39.77 | 42.25 | 37.77 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint EPILEPTIC_SEIZU_RELATED_DRUGS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| EPILEPTIC_SEIZU_RELATED_DRUGS | 5.024 [2.97, 8.51] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 62 out of 360 males with EPILEPTIC_SEIZU_RELATED_DRUGS died.
Mortality risk
Mortality risk for people of age
years, who have EPILEPTIC_SEIZU_RELATED_DRUGS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 1.073% |
| 5 | No data | 6.186% |
| 10 | No data | 14.248% |
| 15 | No data | 25.592% |
| 20 | No data | 40.267% |
Relationships between endpoints
↥Index endpoint: EPILEPTIC_SEIZU_RELATED_DRUGS – Epileptic seizures related to drugs
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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