No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
75 |
4. Check minimum number of eventsNone |
75 |
5. Include endpointsNone |
75 |
6. Filter based on genotype QC (FinnGen only) |
72 |
Control definitions (FinnGen only)
Control exclude
E4_NUTRIDEF
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E50-E64
Name in latin
Sequelae malnutritionis et aliarum deficientiarum nutritionalium
Similar endpoints
↥List of similar endpoints to
Sequelae of malnutrition and other nutritional deficiencies
based on the number of shared cases.
Similar with more cases:
- Other nutritional deficiencies
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1025 | 566 | 443 |
| Only index persons | 738 | 414 | 324 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.02 | 0.01 |
| Only index persons | 0.01 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 73.60 | 76.42 | 70.18 |
| Only index persons | 72.79 | 75.38 | 69.48 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 72 | 32 | 40 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 68.23 | 62.27 | 72.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint E4_SEQUMAL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_SEQUMAL | 2.544 [1.9, 3.41] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.426 |
During the follow-up period (1.1.1998 — 31.12.2019), 307 out of 483 females with E4_SEQUMAL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_SEQUMAL | 3.135 [2.06, 4.76] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 255 out of 380 males with E4_SEQUMAL died.
Mortality risk
Mortality risk for people of age
years, who have E4_SEQUMAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.212% | 0.748% |
| 5 | 1.486% | 4.033% |
| 10 | 3.966% | 9.774% |
| 15 | 7.901% | 17.424% |
| 20 | 13.061% | 28.764% |
Relationships between endpoints
↥Index endpoint: E4_SEQUMAL – Sequelae of malnutrition and other nutritional deficiencies
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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