No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
623 |
4. Check minimum number of eventsNone |
623 |
5. Include endpointsNone |
623 |
6. Filter based on genotype QC (FinnGen only) |
609 |
Control definitions (FinnGen only)
Control exclude
E4_NUTRIDEF
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E61
Name in latin
Sideropenia
Similar endpoints
↥List of similar endpoints to
Iron deficiency
based on the number of shared cases.
Similar with more cases:
- Other nutritional deficiencies
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3324 | 2703 | 601 |
| Only index persons | 2876 | 2502 | 374 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.08 | 0.02 |
| Only index persons | 0.08 | 0.09 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 33.31 | 36.44 | 19.09 |
| Only index persons | 40.25 | 37.72 | 57.20 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 609 | 529 | 80 |
| Unadjusted period prevalence (%) | 0.19 | 0.21 | 0.04 |
| Median age at first event (years) | 42.77 | 40.03 | 60.91 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint E4_FE_DEF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_FE_DEF | 2.095 [1.24, 3.53] | 0.006 |
| Birth year | 0.991 [0.98, 1.0] | 0.05 |
During the follow-up period (1.1.1998 — 31.12.2019), 86 out of 757 females with E4_FE_DEF died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have E4_FE_DEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.187% | No data |
| 5 | 1.011% | No data |
| 10 | 2.722% | No data |
| 15 | 5.249% | No data |
| 20 | 9.096% | No data |
Relationships between endpoints
↥Index endpoint: E4_FE_DEF – Iron deficiency
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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