No definition available.
Postprocedural endocrine and metabolic disorders, not elsewhere classified
EFO MESH Endpoint Browser PheWeb
E4_ENDOMETPOSTOP
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
4613 |
4. Check minimum number of eventsNone |
4613 |
5. Include endpointsNone |
4613 |
6. Filter based on genotype QC (FinnGen only) |
4403 |
Control definitions (FinnGen only)
Control exclude
E4_METABOLIA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E70-E90
Name in latin
Perturbationes endocrinae et metabolicae post interventiones non alibi classificatae
Similar endpoints
↥List of similar endpoints to
Postprocedural endocrine and metabolic disorders, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Other metabolic disorders
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 24717 | 19645 | 4902 |
| Only index persons | 22223 | 17885 | 4338 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.48 | 0.56 | 0.14 |
| Only index persons | 0.56 | 0.66 | 0.17 |
| Median age at first event (years) | |||
| Whole population | 58.32 | 58.68 | 56.98 |
| Only index persons | 56.84 | 57.02 | 56.09 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4403 | 3599 | 804 |
| Unadjusted period prevalence (%) | 1.23 | 1.41 | 0.40 |
| Median age at first event (years) | 52.52 | 51.53 | 56.92 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint E4_ENDOMETPOSTOP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_ENDOMETPOSTOP | 1.389 [1.25, 1.54] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.251 |
During the follow-up period (1.1.1998 — 31.12.2019), 2313 out of 15139 females with E4_ENDOMETPOSTOP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_ENDOMETPOSTOP | 1.759 [1.53, 2.02] | < 0.001 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 856 out of 3787 males with E4_ENDOMETPOSTOP died.
Mortality risk
Mortality risk for people of age
years, who have E4_ENDOMETPOSTOP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.106% | 0.304% |
| 5 | 0.716% | 1.862% |
| 10 | 2.022% | 4.208% |
| 15 | 3.956% | 8.218% |
| 20 | 6.946% | 13.828% |
Relationships between endpoints
↥Index endpoint: E4_ENDOMETPOSTOP – Postprocedural endocrine and metabolic disorders, not elsewhere classified
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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