No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D05
Name in latin
Carcinoma in situ lobulare mammae
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of breast, lobular
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of breast, lobular
- In situ neoplasms
- In situ neoplasms
- Neoplasms
- Any operation in hilmo
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1248 | 1248 | - |
| Only index persons | 1180 | 1180 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | - |
| Only index persons | 0.04 | 0.04 | - |
| Median age at first event (years) | |||
| Whole population | - | 58.52 | - |
| Only index persons | - | 58.36 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 207 | 207 | - |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | - |
| Median age at first event (years) | 57.72 | 57.72 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_INSITU_BREAST_LOBULAR_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_INSITU_BREAST_LOBULAR_EXALLC | 1.277 [1.05, 1.55] | 0.013 |
| Birth year | 0.998 [0.99, 1.01] | 0.56 |
During the follow-up period (1.1.1998 — 31.12.2019), 162 out of 1098 females with CD2_INSITU_BREAST_LOBULAR_EXALLC died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have CD2_INSITU_BREAST_LOBULAR_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.128% | No data |
| 5 | 0.737% | No data |
| 10 | 2.168% | No data |
| 15 | 4.014% | No data |
| 20 | 7.071% | No data |
Relationships between endpoints
↥Index endpoint: CD2_INSITU_BREAST_LOBULAR_EXALLC – Carcinoma in situ of breast, lobular
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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