Benign neoplasm: Vagina

CD2_BENIGN_VULVA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D28.1&
  • Hospital discharge: ICD-9 2211
  • Hospital discharge: ICD-8 2211
  • Cause of death: ICD-10 D28.1&
  • Cause of death: ICD-9 2211
  • Cause of death: ICD-8 2211

2 out of 7 registries used, show all original rules.

407

4. Check minimum number of events

None

407

5. Include endpoints

None

407

6. Filter based on genotype QC (FinnGen only)

399

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D28
Name in latin Neoplasma benignum vaginae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3069 3069 -
Only index persons 2824 2824 -
Unadjusted period prevalence (%)
Whole population 0.09 0.09 -
Only index persons 0.10 0.10 -
Median age at first event (years)
Whole population - 42.47 -
Only index persons - 41.39 -

-FinnGen-

Key figures

All Female Male
Number of individuals 399 399 -
Unadjusted period prevalence (%) 0.16 0.16 -
Median age at first event (years) 41.85 41.85 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_VULVA and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_VULVA 0.972 [0.81, 1.17] 0.766
Birth year 0.997 [0.99, 1.01] 0.428

During the follow-up period (1.1.1998 — 31.12.2019), 141 out of 1498 females with CD2_BENIGN_VULVA died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_VULVA.

N-year risk Females Males
1 0.098% No data
5 0.585% No data
10 1.502% No data
15 3.023% No data
20 5.108% No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_VULVA – Benign neoplasm: Vagina

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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