vulvar carcinoma: A carcinoma that arises from epithelial cells of the mammalian vulva
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
678 |
4. Check minimum number of eventsNone |
678 |
5. Include endpointsNone |
678 |
6. Filter based on genotype QC (FinnGen only) |
651 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D28
Name in latin
Neoplasma benignum vulvae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Vulva
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Vulva
- Benign neoplasm of other and unspecified female genital organs
- Benign neoplasm of other and unspecified female genital organs
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5127 | 5127 | - |
| Only index persons | 4729 | 4729 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.15 | - |
| Only index persons | 0.17 | 0.17 | - |
| Median age at first event (years) | |||
| Whole population | - | 42.27 | - |
| Only index persons | - | 41.49 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 651 | 651 | - |
| Unadjusted period prevalence (%) | 0.26 | 0.26 | - |
| Median age at first event (years) | 41.70 | 41.70 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_VAGINA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_VAGINA | 0.981 [0.85, 1.14] | 0.799 |
| Birth year | 0.997 [0.99, 1.01] | 0.46 |
During the follow-up period (1.1.1998 — 31.12.2019), 326 out of 2726 females with CD2_BENIGN_VAGINA died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_VAGINA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.083% | No data |
| 5 | 0.496% | No data |
| 10 | 1.422% | No data |
| 15 | 2.908% | No data |
| 20 | 5.287% | No data |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_VAGINA – Benign neoplasm: Vulva
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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