No definition available.
Benign neoplasm: Pituitary gland, craniopharyngeal duct
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_PITUITARY_CRANIPHAR
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1736 |
4. Check minimum number of eventsNone |
1736 |
5. Include endpointsNone |
1736 |
6. Filter based on genotype QC (FinnGen only) |
1666 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Pituitary gland, craniopharyngeal duct
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Pituitary gland, craniopharyngeal duct
- Benign neoplasm of other and unspecified endocrine glands
- Benign neoplasm of other and unspecified endocrine glands
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10221 | 5749 | 4361 |
| Only index persons | 9206 | 5345 | 3861 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.16 | 0.12 |
| Only index persons | 0.18 | 0.20 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 50.74 | 47.54 | 55.24 |
| Only index persons | 49.72 | 46.32 | 54.42 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1666 | 980 | 686 |
| Unadjusted period prevalence (%) | 0.37 | 0.38 | 0.34 |
| Median age at first event (years) | 50.44 | 46.57 | 55.96 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_PITUITARY_CRANIPHAR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PITUITARY_CRANIPHAR | 1.615 [1.4, 1.86] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.242 |
During the follow-up period (1.1.1998 — 31.12.2019), 512 out of 4286 females with CD2_BENIGN_PITUITARY_CRANIPHAR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PITUITARY_CRANIPHAR | 1.312 [1.15, 1.5] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 610 out of 3161 males with CD2_BENIGN_PITUITARY_CRANIPHAR died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_PITUITARY_CRANIPHAR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.146% | 0.276% |
| 5 | 0.905% | 1.452% |
| 10 | 2.203% | 3.392% |
| 15 | 4.48% | 6.597% |
| 20 | 7.905% | 11.263% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_PITUITARY_CRANIPHAR – Benign neoplasm: Pituitary gland, craniopharyngeal duct
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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