No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
330 |
4. Check minimum number of eventsNone |
330 |
5. Include endpointsNone |
330 |
6. Filter based on genotype QC (FinnGen only) |
323 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D35
Name in latin
Neoplasma benignum glandulae parathyreoideae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Parathyroid gland
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Parathyroid gland
- Benign neoplasm of other and unspecified endocrine glands
- Benign neoplasm of other and unspecified endocrine glands
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2464 | 1832 | 617 |
| Only index persons | 2183 | 1635 | 548 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.02 |
| Only index persons | 0.05 | 0.06 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 63.70 | 64.32 | 61.99 |
| Only index persons | 62.91 | 63.38 | 61.51 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 323 | 227 | 96 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.05 |
| Median age at first event (years) | 60.49 | 59.82 | 62.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_PARATHYROID and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PARATHYROID | 1.159 [1.0, 1.35] | 0.058 |
| Birth year | 0.995 [0.99, 1.0] | 0.266 |
During the follow-up period (1.1.1998 — 31.12.2019), 274 out of 1306 females with CD2_BENIGN_PARATHYROID died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PARATHYROID | 1.321 [1.02, 1.71] | 0.035 |
| Birth year | 0.989 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 462 males with CD2_BENIGN_PARATHYROID died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_PARATHYROID.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.131% | 0.225% |
| 5 | 0.641% | 1.462% |
| 10 | 1.589% | 3.921% |
| 15 | 3.173% | 7.784% |
| 20 | 5.666% | 13.282% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_PARATHYROID – Benign neoplasm: Parathyroid gland
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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