Other benign neoplasm of uterus: Corpus uteri

CD2_BENIGN_CORPUS_UTERI

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D26.1&
  • Hospital discharge: ICD-9 2191
  • Cause of death: ICD-10 D26.1&
  • Cause of death: ICD-9 2191

2 out of 7 registries used, show all original rules.

231

4. Check minimum number of events

None

231

5. Include endpoints

None

231

6. Filter based on genotype QC (FinnGen only)

219

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D26
Name in latin Neoplasma benignum corporis uteri

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1799 1799 -
Only index persons 1700 1700 -
Unadjusted period prevalence (%)
Whole population 0.05 0.05 -
Only index persons 0.06 0.06 -
Median age at first event (years)
Whole population - 49.00 -
Only index persons - 48.68 -

-FinnGen-

Key figures

All Female Male
Number of individuals 219 219 -
Unadjusted period prevalence (%) 0.09 0.09 -
Median age at first event (years) 46.87 46.87 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_CORPUS_UTERI and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_CORPUS_UTERI 1.1 [0.88, 1.37] 0.399
Birth year 0.993 [0.98, 1.0] 0.102

During the follow-up period (1.1.1998 — 31.12.2019), 99 out of 929 females with CD2_BENIGN_CORPUS_UTERI died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CORPUS_UTERI.

N-year risk Females Males
1 0.113% No data
5 0.59% No data
10 1.357% No data
15 2.656% No data
20 4.619% No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_CORPUS_UTERI – Other benign neoplasm of uterus: Corpus uteri

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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