Other benign neoplasm of uterus: Cervix uteri

CD2_BENIGN_CERVIX_UTERI

cervical carcinoma: A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are: squamous carcinoma, adenocarcinoma, adenosquamous carcinoma, adenoid cystic carcinoma and undifferentiated carcinoma.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D26.0&
  • Hospital discharge: ICD-9 2190
  • Cause of death: ICD-10 D26.0&
  • Cause of death: ICD-9 2190

2 out of 7 registries used, show all original rules.

185

4. Check minimum number of events

None

185

5. Include endpoints

None

185

6. Filter based on genotype QC (FinnGen only)

180

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D26
Name in latin Neoplasma benignum cervicis uteri

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1668 1668 -
Only index persons 1538 1538 -
Unadjusted period prevalence (%)
Whole population 0.05 0.05 -
Only index persons 0.06 0.06 -
Median age at first event (years)
Whole population - 47.87 -
Only index persons - 47.37 -

-FinnGen-

Key figures

All Female Male
Number of individuals 180 180 -
Unadjusted period prevalence (%) 0.07 0.07 -
Median age at first event (years) 47.30 47.30 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_CERVIX_UTERI and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_CERVIX_UTERI 1.246 [0.97, 1.6] 0.081
Birth year 0.996 [0.99, 1.0] 0.33

During the follow-up period (1.1.1998 — 31.12.2019), 75 out of 822 females with CD2_BENIGN_CERVIX_UTERI died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CERVIX_UTERI.

N-year risk Females Males
1 0.128% No data
5 0.776% No data
10 2.011% No data
15 3.774% No data
20 6.605% No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_CERVIX_UTERI – Other benign neoplasm of uterus: Cervix uteri

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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