No definition available.
Adenocarcinoma and papillary adenocarcinoma of stomach
C3_STOMACH_ADENO_EXALLC
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
First used in FinnGen datafreeze
DF8
Similar endpoints
↥List of similar endpoints to
Adenocarcinoma and papillary adenocarcinoma of stomach
based on the number of shared cases.
Similar with more cases:
- Adenocarcinoma and papillary adenocarcinoma of stomach
- Malignant neoplasm of stomach
- Malignant neoplasm of stomach
- Malignant neoplasm of digestive organs
- Malignant neoplasm of digestive organs
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 21290 | 8038 | 12515 |
| Only index persons | 6021 | 2608 | 3413 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.32 | 0.23 | 0.35 |
| Only index persons | 0.12 | 0.10 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 68.21 | 69.57 | 67.44 |
| Only index persons | 68.99 | 69.66 | 68.49 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 956 | 267 | 689 |
| Unadjusted period prevalence (%) | 0.28 | 0.10 | 0.35 |
| Median age at first event (years) | 67.78 | 65.19 | 68.79 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint C3_STOMACH_ADENO_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_STOMACH_ADENO_EXALLC | 8.714 [7.17, 10.59] | < 0.001 |
| Birth year | 0.997 [0.99, 1.0] | 0.44 |
During the follow-up period (1.1.1998 — 31.12.2019), 2836 out of 3427 females with C3_STOMACH_ADENO_EXALLC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_STOMACH_ADENO_EXALLC | 7.581 [6.2, 9.27] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 4052 out of 4755 males with C3_STOMACH_ADENO_EXALLC died.
Mortality risk
Mortality risk for people of age
years, who have C3_STOMACH_ADENO_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.858% | 1.483% |
| 5 | 4.502% | 9.026% |
| 10 | 11.305% | 20.105% |
| 15 | 21.79% | 35.574% |
| 20 | 36.455% | 52.607% |
Relationships between endpoints
↥Index endpoint: C3_STOMACH_ADENO_EXALLC – Adenocarcinoma and papillary adenocarcinoma of stomach
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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