No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF9
Similar endpoints
↥List of similar endpoints to
Serous cystic and papillary carcinoma
based on the number of shared cases.
Similar with more cases:
- Serous carcinoma of ovary
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9850 | 9850 | - |
| Only index persons | 6307 | 6307 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.28 | 0.28 | - |
| Only index persons | 0.23 | 0.23 | - |
| Median age at first event (years) | |||
| Whole population | - | 63.82 | - |
| Only index persons | - | 64.78 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1016 | 1016 | - |
| Unadjusted period prevalence (%) | 0.40 | 0.40 | - |
| Median age at first event (years) | 64.73 | 64.73 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint C3_OVARY_SEROUS_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_OVARY_SEROUS_EXALLC | 8.29 [7.34, 9.37] | < 0.001 |
| Birth year | 0.997 [0.99, 1.0] | 0.42 |
During the follow-up period (1.1.1998 — 31.12.2019), 4257 out of 6621 females with C3_OVARY_SEROUS_EXALLC died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have C3_OVARY_SEROUS_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.739% | No data |
| 5 | 4.458% | No data |
| 10 | 11.12% | No data |
| 15 | 20.547% | No data |
| 20 | 34.531% | No data |
Relationships between endpoints
↥Index endpoint: C3_OVARY_SEROUS_EXALLC – Serous cystic and papillary carcinoma
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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