No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF9
Name in latin
Carcinoma in situ labii (oris)
Similar endpoints
↥List of similar endpoints to
Chromophobe cell carcinoma of kidney
based on the number of shared cases.
Similar with more cases:
- Chromophobe cell carcinoma of kidney
- Renal cell carcinoma of kidney
- Renal cell carcinoma of kidney
- Malignant neoplasm of kidney, except renal pelvis
- Malignant neoplasm of kidney, except renal pelvis
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 531 | 219 | 312 |
| Only index persons | 525 | 217 | 308 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | - | 66.09 | 69.81 |
| Only index persons | 68.28 | 66.09 | 69.81 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 143 | 52 | 91 |
| Unadjusted period prevalence (%) | 0.04 | 0.02 | 0.05 |
| Median age at first event (years) | 67.66 | 63.81 | 69.86 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint C3_KIDNEY_CHROMOPHOBE_EXALLC and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_KIDNEY_CHROMOPHOBE_EXALLC | 1.412 [0.91, 2.19] | 0.125 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 272 males with C3_KIDNEY_CHROMOPHOBE_EXALLC died.
Mortality risk
Mortality risk for people of age
years, who have C3_KIDNEY_CHROMOPHOBE_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.227% |
| 5 | No data | 1.735% |
| 10 | No data | 4.124% |
| 15 | No data | 7.451% |
| 20 | No data | 12.177% |
Relationships between endpoints
↥Index endpoint: C3_KIDNEY_CHROMOPHOBE_EXALLC – Chromophobe cell carcinoma of kidney
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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