No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
First used in FinnGen datafreeze
DF8
Similar endpoints
↥List of similar endpoints to
Gastrointestinal stromal tumor and sarcoma
based on the number of shared cases.
Similar with more cases:
- Gastrointestinal stromal tumor and sarcoma
- Any event in cancer register
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 664 | 292 | 368 |
| Only index persons | 533 | 240 | 293 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 68.22 | 69.05 | 67.60 |
| Only index persons | 68.51 | 69.64 | 67.58 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 328 | 155 | 173 |
| Unadjusted period prevalence (%) | 0.07 | 0.06 | 0.09 |
| Median age at first event (years) | 67.03 | 65.29 | 68.59 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint C3_GASTRINT_STROM_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_GASTRINT_STROM_EXALLC | 3.01 [2.15, 4.22] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.02 |
During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 226 females with C3_GASTRINT_STROM_EXALLC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_GASTRINT_STROM_EXALLC | 2.872 [2.1, 3.93] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.044 |
During the follow-up period (1.1.1998 — 31.12.2019), 136 out of 266 males with C3_GASTRINT_STROM_EXALLC died.
Mortality risk
Mortality risk for people of age
years, who have C3_GASTRINT_STROM_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.274% | 0.498% |
| 5 | 1.509% | 3.328% |
| 10 | 3.399% | 8.718% |
| 15 | 6.49% | 15.698% |
| 20 | 11.354% | 26.173% |
Relationships between endpoints
↥Index endpoint: C3_GASTRINT_STROM_EXALLC – Gastrointestinal stromal tumor and sarcoma
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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