No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
First used in FinnGen datafreeze
DF8
Similar endpoints
↥List of similar endpoints to
Squamous cell neoplasms and carcinoma of cervix
based on the number of shared cases.
Similar with more cases:
- Squamous cell neoplasms and carcinoma of cervix
- Malignant neoplasm of cervix uteri
- Malignant neoplasm of cervix uteri
- malignant neoplasm of female genital organs
- malignant neoplasm of female genital organs
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4958 | 4958 | - |
| Only index persons | 2298 | 2298 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.14 | - |
| Only index persons | 0.08 | 0.08 | - |
| Median age at first event (years) | |||
| Whole population | - | 50.31 | - |
| Only index persons | - | 45.24 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 212 | 212 | - |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | - |
| Median age at first event (years) | 42.71 | 42.71 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint C3_CERVIX_SQUAM_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_CERVIX_SQUAM_EXALLC | 4.528 [3.66, 5.61] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.527 |
During the follow-up period (1.1.1998 — 31.12.2019), 647 out of 1643 females with C3_CERVIX_SQUAM_EXALLC died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have C3_CERVIX_SQUAM_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.632% | No data |
| 5 | 2.992% | No data |
| 10 | 7.255% | No data |
| 15 | 13.26% | No data |
| 20 | 22.822% | No data |
Relationships between endpoints
↥Index endpoint: C3_CERVIX_SQUAM_EXALLC – Squamous cell neoplasms and carcinoma of cervix
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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