No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
First used in FinnGen datafreeze
DF8
Similar endpoints
↥List of similar endpoints to
Adenocarcinomas of cervix
based on the number of shared cases.
Similar with more cases:
- Adenocarcinomas of cervix
- Malignant neoplasm of cervix uteri
- Malignant neoplasm of cervix uteri
- malignant neoplasm of female genital organs
- malignant neoplasm of female genital organs
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1511 | 1511 | - |
| Only index persons | 979 | 979 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | - |
| Only index persons | 0.04 | 0.04 | - |
| Median age at first event (years) | |||
| Whole population | - | 50.28 | - |
| Only index persons | - | 46.04 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 146 | 146 | - |
| Unadjusted period prevalence (%) | 0.06 | 0.06 | - |
| Median age at first event (years) | 42.97 | 42.97 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint C3_CERVIX_ADENO_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_CERVIX_ADENO_EXALLC | 5.724 [4.3, 7.62] | < 0.001 |
| Birth year | 1.001 [0.99, 1.01] | 0.783 |
During the follow-up period (1.1.1998 — 31.12.2019), 272 out of 782 females with C3_CERVIX_ADENO_EXALLC died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have C3_CERVIX_ADENO_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.625% | No data |
| 5 | 3.906% | No data |
| 10 | 9.772% | No data |
| 15 | 18.581% | No data |
| 20 | 30.328% | No data |
Relationships between endpoints
↥Index endpoint: C3_CERVIX_ADENO_EXALLC – Adenocarcinomas of cervix
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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