Autoimmune diseases excluding thyroid diseases, strict definition

AUTOIMMUNE_NONTHYROID_STRICT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

  • not (HYPOTHY_LEVOTHY
  • or GRAVES_COND
  • or E4_HYTHY_AI_STRICT
  • or AUTOIMMUNE_HYPERTHYROIDISM
411993

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

64657

6. Filter based on genotype QC (FinnGen only)

62294

Control definitions (FinnGen only)

Control conditions not (HYPOTHY_LEVOTHY
or GRAVES_COND
or E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM

Extra metadata

First used in FinnGen datafreeze DF7

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 62294 33088 29206
Unadjusted period prevalence (%) 13.78 13.00 14.67
Median age at first event (years) 46.90 44.30 49.85

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AUTOIMMUNE_NONTHYROID_STRICT – Autoimmune diseases excluding thyroid diseases, strict definition

GWS hits: 57

This endpoint is excluded (different definition than used in FinnGen).