No definition available.
Human immunodeficiency virus [HIV] disease resulting in other conditions
AB1_OTHER_CONDITIONS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
590 |
4. Check minimum number of eventsNone |
590 |
5. Include endpointsNone |
590 |
6. Filter based on genotype QC (FinnGen only) |
479 |
Control definitions (FinnGen only)
Control exclude
AB1_HIV
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Human immunodeficiency virus [HIV] disease resulting in other conditions
based on the number of shared cases.
Similar with more cases:
- Human immunodeficiency virus [HIV] disease
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2761 | 677 | 1897 |
| Only index persons | 2352 | 643 | 1709 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.02 | 0.05 |
| Only index persons | 0.05 | 0.02 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 37.99 | 33.57 | 39.95 |
| Only index persons | 38.02 | 33.45 | 39.74 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 479 | 92 | 387 |
| Unadjusted period prevalence (%) | 0.16 | 0.04 | 0.19 |
| Median age at first event (years) | 39.79 | 39.15 | 39.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint AB1_OTHER_CONDITIONS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_OTHER_CONDITIONS | 4.108 [2.91, 5.8] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.455 |
During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 643 females with AB1_OTHER_CONDITIONS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_OTHER_CONDITIONS | 2.837 [2.42, 3.32] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.018 |
During the follow-up period (1.1.1998 — 31.12.2019), 266 out of 1729 males with AB1_OTHER_CONDITIONS died.
Mortality risk
Mortality risk for people of age
years, who have AB1_OTHER_CONDITIONS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.439% | 0.538% |
| 5 | 2.69% | 3.498% |
| 10 | 5.971% | 8.836% |
| 15 | 12.195% | 15.784% |
| 20 | 20.703% | 25.317% |
Relationships between endpoints
↥Index endpoint: AB1_OTHER_CONDITIONS – Human immunodeficiency virus [HIV] disease resulting in other conditions
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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